Difloxacin hydrochloride (CAS 91296-86-5) is a white crystalline powder widely used in veterinary medicine as a fluoroquinolone antibiotic API. It is recognized for its broad-spectrum antibacterial activity against both Gram-negative and Gram-positive bacteria, making it an essential raw material for companion animal and livestock formulations.

Difloxacin HCL is primarily used to treat respiratory, urinary tract, and skin infections in dogs, cats, and livestock. Its high purity, stability, and veterinary-grade quality make it a reliable choice for veterinary pharmaceutical manufacturers seeking consistent efficacy and safety in their products.

Chemical and Quality Information

• CAS Number: 91296-86-5

• Molecular Formula: C₂₀H₂₀FN₃O₃·HCl

• Molecular Weight: 387.85 g/mol

• Appearance: White crystalline powder

• Purity: ≥98% by HPLC

• Solubility: Soluble in water and organic solvents such as methanol

• Storage: Store in a cool, dry place, protected from light and moisture

• Standards: GMP-compliant, USP/EP/BP certified

Each batch of Difloxacin HCL is supplied with a Certificate of Analysis (COA) and Safety Data Sheet (SDS) to ensure regulatory compliance, traceability, and quality assurance for veterinary pharmaceutical production.

Function and Application
Difloxacin HCL is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, preventing bacterial replication and growth. It is used in:

• Companion animals: Dogs and cats suffering from urinary tract infections, skin infections, or respiratory diseases.

• Livestock: Cattle, pigs, and sheep requiring treatment for bacterial infections impacting health and productivity.

Dosage forms include tablets, capsules, and oral suspensions, allowing veterinarians and manufacturers to create versatile treatment solutions. Difloxacin HCL is often formulated in combination with other veterinary APIs to broaden the spectrum of activity while maintaining high efficacy.

Practical Usage Tips

• Follow veterinary prescription guidelines for proper dosing; overdosing may lead to adverse effects.

• Ensure uniform dispersion in feed premixes or liquid formulations.

• Avoid simultaneous administration with other drugs that may interfere with absorption or activity.

• Store in airtight, moisture-proof containers to maintain crystalline integrity.

• Monitor bacterial sensitivity to avoid resistance development, especially in farm animals.

Industry and Market Advantages
Difloxacin HCL’s broad-spectrum activity, high bioavailability, and predictable pharmacokinetics make it a preferred veterinary API for manufacturers. It is suitable for both preventive and therapeutic applications, supporting the health of pets and livestock. Key benefits include:

• Reliable GMP-certified production ensuring batch-to-batch consistency

• Compliance with USP/EP/BP standards for international markets

• Applicability across multiple animal species and disease indications

• Support for combination therapies with other veterinary APIs

Research Insights
Studies indicate that Difloxacin HCL rapidly reduces bacterial load in infected animals, leading to improved recovery and reduced complications. In livestock, its inclusion in veterinary formulations helps maintain herd health, reduce economic losses, and improve overall productivity.

Global Supply from Arshine Lifescience
At Arshine Lifescience, we provide Difloxacin HCL API with high purity and GMP certification, ready for global veterinary pharmaceutical markets. We supply bulk quantities with full documentation (COA, SDS, GMP certificates) to ensure that manufacturers worldwide can produce effective, compliant, and safe veterinary antibiotic products.

Whether producing companion animal medications or livestock health formulations, Arshine Lifescience guarantees consistent quality, reliable supply, and worldwide delivery.

Conclusion
Difloxacin HCL is a versatile and essential veterinary API for treating bacterial infections in companion animals and livestock. With proven efficacy, high purity, and global supply capabilities from Arshine Lifescience, manufacturers and veterinarians can confidently formulate and administer reliable, safe, and effective treatments.

Keywords Embedded: Difloxacin HCL API, Veterinary fluoroquinolone API, Animal antibacterial API, Veterinary drug ingredient, CAS 91296-86-5, GMP veterinary API, Companion animal infection API, Livestock antibiotic API