Milbemycin (CAS 101831-37-2) is a white crystalline powder widely used as a veterinary antiparasitic API for companion animals and livestock. Known for its high purity and stability, Milbemycin is a critical ingredient for veterinary pharmaceutical manufacturers aiming to produce effective antiparasitic treatments.

As a broad-spectrum veterinary API, Milbemycin demonstrates activity against gastrointestinal nematodes, heartworms, and other endoparasites, making it indispensable in animal health formulations for dogs, cats, cattle, and small ruminants. Its inclusion in veterinary products helps maintain animal welfare, prevent disease outbreaks, and enhance growth performance in livestock.

Chemical and Quality Information

• CAS Number: 101831-37-2

• Molecular Formula: C₃₁H₄₉NO₇

• Molecular Weight: 567.73 g/mol

• Appearance: White crystalline powder

• Purity: ≥98% by HPLC

• Solubility: Slightly soluble in water, soluble in organic solvents such as methanol and DMSO

• Storage: Keep in a cool, dry, and dark place; avoid moisture and light exposure

• Standards: GMP-compliant, USP/EP/BP specifications

Milbemycin API is supplied with COA and SDS, ensuring quality assurance, regulatory compliance, and traceability. These certifications provide confidence to vet pharma API suppliers and manufacturers who require consistent performance in their veterinary formulations.

Function and Application
Milbemycin acts as a macrocyclic lactone antiparasitic agent, effectively targeting:

• Endoparasites: gastrointestinal nematodes such as roundworms and hookworms

• Heartworms: prevention and treatment in dogs

• Other parasitic infections in livestock, including sheep, goats, and cattle

Milbemycin API is suitable for various dosage forms, including tablets, oral suspensions, and feed premixes. In companion animals, tablets containing Milbemycin are commonly administered as part of heartworm prevention programs, often combined with other veterinary APIs for broader parasite control. In livestock, it is formulated in feed premixes to maintain herd health, reduce parasitic burden, and improve productivity.

Practical Usage Tips

• Dosage: Must follow veterinary prescription guidelines based on species and weight. Overdose may lead to adverse reactions.

• Administration: Ensure thorough mixing when incorporated into feed premixes to guarantee uniform distribution.

• Compatibility: Can be combined with other veterinary APIs, but pre-formulation testing is recommended to ensure stability.

• Storage: Protect from moisture and high temperatures to preserve efficacy.

• Monitoring: Regular parasitic monitoring in animals is recommended to optimize treatment schedules and prevent resistance development.

Industry and Market Advantages
Milbemycin’s broad-spectrum efficacy and proven safety profile make it a preferred veterinary pharmaceutical raw material. Manufacturers value it for:

• Reliable batch-to-batch consistency under GMP production

• Compliance with USP/EP/BP standards, meeting global regulatory requirements

• Versatility across multiple animal species and dosage forms

• High bioavailability and efficacy for both preventive and therapeutic applications

Veterinary product developers often use Milbemycin API in combination with other antiparasitic agents to create combination therapies, enhancing spectrum of activity while maintaining regulatory compliance.

Research Insights
Scientific studies show that Milbemycin is highly effective in reducing parasite load in dogs and livestock. It demonstrates a rapid onset of action against nematodes and heartworm larvae, which translates into faster recovery, improved animal health, and reduced economic losses for livestock producers.

Global Supply and Purchasing Information
At Arshine Lifescience, we provide Milbemycin API in bulk quantities with full documentation, including COA, SDS, and GMP certification. Our supply chain is designed to support global veterinary pharmaceutical manufacturers, ensuring consistent quality and reliable delivery. Customers worldwide can access high-purity Milbemycin suitable for tablets, oral suspensions, or feed premixes.

Whether producing companion animal medications or livestock health products, Arshine Lifescience offers the expertise and supply reliability needed to maintain production continuity and regulatory compliance.

Conclusion
Milbemycin API is an essential ingredient for broad-spectrum antiparasitic formulations in veterinary medicine. Its efficacy, safety, and versatility make it highly valued by manufacturers and veterinarians alike. By sourcing from Arshine Lifescience, global customers gain access to high-quality, GMP-certified Milbemycin suitable for a wide range of veterinary applications, ensuring healthier animals and optimized production outcomes.