Penicillin G Procain

Penicillin G Procaine

Penicillin G Procaine is a long-acting beta-lactam antibiotic extensively used in veterinary medicine for the effective management of infections caused by Gram-positive bacteria. It functions by inhibiting bacterial cell wall synthesis, making it highly potent against pathogens such as Streptococcus, Staphylococcus, Clostridium, and Erysipelothrix rhusiopathiae. Due to its unique formulation, it acts as a depot injection, releasing penicillin slowly into the bloodstream to maintain therapeutic levels for up to 24 hours. This makes it a standard treatment for shipping fever in cattle, swine erysipelas, equine strangles, and respiratory tract infections like pneumonia. Available as a sterile injectable suspension, Penicillin G Procaine is often synonymous with reliable, cost-effective control of systemic infections and is frequently combined with Dihydrostreptomycin (Pen-Strep) to broaden its antibacterial spectrum.

FAQ（Penicillin G Procaine）

1. What is Penicillin G Procaine used for?
It is primarily used to treat infections caused by penicillin-susceptible Gram-positive bacteria, including bacterial pneumonia, mastitis, metritis, swine erysipelas, and wound infections (such as Blackleg).

2. How is Penicillin G Procaine administered?
It is strictly administered via deep intramuscular injection (IM). It must never be given intravenously (IV) to avoid severe toxic reactions to procaine. The suspension should be shaken well before use.

3. Which animals can use Penicillin G Procaine?
It is widely used for cattle (beef and dairy), swine (pigs), sheep, and horses; it is also used for companion animals like dogs and cats for specific bacterial conditions.

4. Is Penicillin G Procaine safe for livestock?
Yes, it is generally safe but requires adherence to strict withdrawal periods for meat and milk to prevent antibiotic residues. Caution is needed in animals with known penicillin allergies.

5. Can Penicillin G Procaine be combined with other drugs?
Yes, it is frequently formulated with Dihydrostreptomycin (creating "Pen-Strep") to provide broad-spectrum coverage against both Gram-positive and Gram-negative bacteria during severe mixed infections.