Maropitant (CAS 147116-67-4) is a white to off-white crystalline powder used as a veterinary anti-emetic API for dogs and cats. It is highly effective in preventing and treating vomiting and nausea, including motion sickness, chemotherapy-induced vomiting, and gastroenteritis. As a high-purity veterinary API, Maropitant supports the formulation of tablets, injectable solutions, and oral suspensions in companion animal pharmaceuticals.

Chemical and Quality Information

• CAS Number: 147116-67-4

• Molecular Formula: C₂₇H₃₀F₂N₂O₄

• Molecular Weight: 476.54 g/mol

• Appearance: White to off-white crystalline powder

• Purity: ≥98% by HPLC

• Solubility: Slightly soluble in water, soluble in organic solvents like DMSO

• Storage: Store in a cool, dry place, protected from light and moisture

• Standards: GMP-certified, USP/EP/BP compliant

Each batch comes with COA and SDS, ensuring quality assurance and regulatory compliance for global veterinary pharmaceutical use.

Function and Application
Maropitant acts as a neurokinin-1 (NK1) receptor antagonist, effectively blocking substance P to prevent vomiting. Its applications include:

• Companion animals: Dogs and cats suffering from nausea due to gastrointestinal disorders, chemotherapy, or motion sickness

• Dosage forms: Tablets, oral suspensions, and injectable solutions for flexible administration

By incorporating Maropitant API into formulations, veterinarians can manage acute and chronic vomiting, improve animal welfare, and enhance treatment adherence in pets.

Practical Usage Tips

• Follow veterinary dosage guidelines based on weight and condition

• Avoid concurrent use with drugs that may interfere with metabolism

• Store in airtight, light-protected containers to maintain potency

• Monitor response and adjust dosing as required under veterinary supervision

Industry and Market Advantages
Maropitant’s efficacy, safety, and versatility make it a valuable veterinary pharmaceutical raw material. Benefits include:

• Reliable GMP-certified production ensuring consistent quality

• Compliance with USP/EP/BP standards for international distribution

• Suitability for tablets, oral suspensions, and injectable formulations

• Support for pet pharmaceutical manufacturers in developing innovative anti-emetic products

Research Insights
Clinical studies show Maropitant provides rapid relief from nausea and vomiting, improving recovery and quality of life in dogs and cats. Its inclusion in veterinary formulations also reduces stress in pets during treatment and enhances compliance in multi-dose regimens.

Global Supply from Arshine Lifescience
Arshine Lifescience provides Maropitant API globally, offering high-purity, GMP-certified products with full documentation (COA, SDS). Manufacturers can formulate tablets, oral suspensions, or injectables to address vomiting and nausea in companion animals worldwide.

Conclusion
Maropitant is a key veterinary API for managing vomiting and nausea in pets. With Arshine Lifescience as a reliable supplier, manufacturers gain access to high-quality, globally available API suitable for safe and effective veterinary formulations.

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